Impacts of the Earth’s 7 billion people are changing the evolutionary processes that underlay and maintain diversity. As a consequence, we are witnessing a global, but unplanned, evolutionary experiment with the planet’s biotic diversity. Growing empirical evidence indicates that human-induced evolutionary changes are rapidly impacting every corner of the globe. CTR researchers are working to understand how human activities are affecting the evolutionary processes that generate and maintain diversity on the planet. This includes how climate change effects disease. We are documenting the consequences of human-induced changes in evolutionary processes as well as studying ways to mitigate these consequences.